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Effectiveness and Safety of Chronic Migraine Preventive Treatments: A Systematic Literature Review - PubMed

Effectiveness and Safety of Chronic Migraine Preventive Treatments: A Systematic Literature Review - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/36417165/

doi: 10.1007/s40122-022-00452-3. Online ahead of print. 1 The Los Angeles and San Diego Headache Centers, San Diego, CA, USA. 2 Bridge Medical Consulting Ltd, Richmond, London, UK. 3 AbbVie, 2525 Dupont Drive, Irvine, CA, 92612, USA. [email protected]. 4 AbbVie, 2525 Dupont Drive, Irvine, CA, 92612, USA. 5 Barrow Neurological Institute, Phoenix, AZ, USA.


Conclusions: "Conclusion: While substantial real-world evidence supports the long-term effectiveness and safety of onabotulinumtoxinA, real-world data on other preventive treatments of CM are currently limited to short term effectiveness due to their more recent approvals."


  • December 21, 2022
    Interesting article - Substantial data demonstrated that onabotulinumtoxinA reduces the number/frequency of headaches, concomitant acute medication use, and impact of headaches on well-being and daily activity.
  • December 03, 2022
    This is important to have insurance be on board as well.