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Level of therapeutic innovation from the registration studies of the new drugs for the prophylaxis of migraine - PubMed

Level of therapeutic innovation from the registration studies of the new drugs for the prophylaxis of migraine - PubMed

Source :

https://pubmed.ncbi.nlm.nih.gov/36054749/

The new monoclonal antibodies of the class of CGRP targeting therapies have been authorized with efficacy data only against placebo. They do not offer additional clinical benefits compared to available therapies for the prevention of migraine attacks, with the exception of a lower frequency of admin ...


Discussion: The new monoclonal antibodies of the class of CGRP targeting therapies have been authorized with efficacy data only against placebo. They do not offer additional clinical benefits compared to available therapies for the prevention of migraine attacks, with the exception of a lower frequency of administration and a more rapid effect. All this assigns to these drugs only a modest role in therapy according to our algorithm for therapeutic innovation with a significantly higher cost than similar therapies.