Close to 25% of migraine patients don’t respond to triptans. Many have contraindications (coronary disease, etc.) to triptans or to their alternatives (such as NSAIDs in patients on anticoagulation, etc.)... So, I’m very excited for the NEW migraine abortive gepant class with Ubrelvy (Ubrogepant)! This is a calcitonin gene-related peptide (CGRP) receptor antagonist. It is not a migraine preventative monoclonal CGRP antibody treatment such as Aimovig, Ajovy, or Emgality. It is indicated for the acute treatment of migraine with or without aura in adults. Patients can get it for $10 a month, which is great way for them to be able to trial it. Most pharmacies are now carrying it.
Source : https://www.ubrelvy.com/home