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Clinical, oculographic, and vestibular test characteristics of vestibular migraine - Allison S Young, Benjamin Nham, Andrew P Bradshaw, Zeljka Calic, Jacob M Pogson, Mario D'Souza, G Michael Halmagyi, Miriam S Welgampola, 2021

Background We characterise the history, vestibular tests, ictal and interictal nystagmus in vestibular migraine. We present our observations on 101 adult-patients presenting to an outpatient facility with recurrent spontaneous and/or ..... see more

Source : https://doi.org/10.1177/03331024211006042

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  • from Doctor Unite 10 hours 27 min
    Further history taking and through evaluation should be done
  • 2 weeks 6 days
    Vestibular migraine can be difficult to diagnose and treat.

Patient with Migraine with Aura Experiences Increasing Symptoms and Risks

History and Present Illness
Patient is a 46-year-old female that was diagnosed with migraine with aura approximately ..... see more

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  • from Doctor Unite 10 hours 28 min
    Triptans should not be recommended
  • from Doctor Unite 1 week 2 days
    Vasculopathology- would use a CGRP inhibitory ie. Emgality prophylaxis and prn CGRP such as Ubrelvy. No triptans.
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Safety and tolerability evaluation of erenumab for the preventive treatment of migraine

Abstract Introduction: Erenumab, a monoclonal antibody targeting the receptor of calcitonin gene related peptide (CGRP), is the first disease-specific and mechanism-based treatment approved for the prevention of migraine. Although the ..... see more

Source : https://www.tandfonline.com/doi/abs/10.1080/14740338.2021.1933941

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A genetic interaction of NRXN2 with GABRE, SYT1 and CASK in migraine patients: a case-control study

Background Migraine is a multifactorial disorder that is more frequent (two to four times) in women than in men. In recent years, our research group has focused on the role ..... see more

Source : https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1186/s10194-021-01266-y

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Voxel-based quantitative susceptibility mapping revealed increased cerebral iron over the whole brain in chronic migraine - Zhiye Chen, Wei Dai, Xiaoyan Chen, Mengqi Liu, Lin Ma, Shengyuan Yu, 2021

Abstract Background The previous documents demonstrated that iron deposition was identified in brain deep nuclei and periaqueductal gray matter region in chronic migraine (CM), and less is known about the ..... see more

Source : https://doi.org/10.1177/17448069211020894

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Awareness of Depression in Patients with Migraine

Migraines comprise a group of neurological symptoms that typically include severe, reoccurring, and throbbing pain on at least one side of the head. I.. see more

Source : https://www.sysrevpharm.org/abstract/awareness-of-depression-in-patients-with-migraine-76459.html

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  • 5 days 3 hours
    Depression is a very important co-morbidity in migraine.
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A Framework for Estimating the Eligible Patient Population for New Migraine Acute Therapies in the United States

Introduction Migraine is associated with considerable disability for patients not adequately managed with current standards of care. New acute therapies may offer relief for this population of patients; however, population ..... see more

Source : https://link.springer.com/article/10.1007/s12325-021-01781-z

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Safety and tolerability evaluation of erenumab for the preventive treatment of migraine

Abstract Introduction: Erenumab, a monoclonal antibody targeting the receptor of calcitonin gene related peptide (CGRP), is the first disease-specific and mechanism-based treatment approved for the prevention of migraine. Although the ..... see more

Source : https://www.tandfonline.com/doi/abs/10.1080/14740338.2021.1933941

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Early use of erenumab in US real-world practice - Alina Bogdanov, Victoria Chia, Mark Bensink, Robert Urman, Lauren Fischer, Soeren Rasmussen, Christine Szekely, Lee Kallenbach, 2021

Background: Erenumab, a monoclonal antibody (mAb) developed to block the calcitonin gene-related peptide (CGRP) receptor, is approved for the prevention of migraine in adults. This retrospective observational study sought to ..... see more

Source : https://journals.sagepub.com/doi/full/10.1177/25158163211020419

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  • 5 days 3 hours
    These are important studies, real world experience.
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DOI: see more

Spontaneous coronary artery dissection and migraine crisis: an exceptional combination in male patients | Letters to the Editor

Home > Letters to the Editor > Spontaneous coronary artery dissection and migraine crisis: an exceptional combination in male patients Available online: 09/21/2020 Disección coronaria espontánea y crisis de migraña: ..... see more

Source : https://doi.org/10.24875/RECICE.M20000158

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  • 5 days 3 hours
    Dissection is seen in migraine but typically in the carotid arteries.
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Hypervigilance, Allostatic Load, and Migraine Prevention: Antibodies to CGRP or Receptor

Migraine involves brain hypersensitivity with episodic dysfunction triggered by behavioral or physiological stressors. During an acute migraine attack the trigeminal nerve is activated (peripheral sensitization). This leads to central sensitization ..... see more

Source : https://link.springer.com/article/10.1007/s40120-021-00250-7

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  • 5 days 4 hours
    cGRP inhibitors are an important development in migraine prevention.
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The efficacy of Alpha‐Lipoic Acid in improving oxidative, inflammatory and mood status in women with episodic migraine in a randomized, double‐blind, placebo‐controlled clinical trial

Migraine is a common neurovascular disorder, which is associated with severe to moderate disabling headaches. Oxidative stress and inflammation might play a role in migraine pathogenesis and the mood disorders. ..... see more

Source : https://onlinelibrary.wiley.com/doi/abs/10.1111/ijcp.14455

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  • 5 days 4 hours
    Oxidative stress can be a contributing factor to migraine.
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Effectiveness and Safety of CGRP-mAbs in Menstrual-Related Migraine: A Real-World Experience

Introduction Migraine shows a significantly higher prevalence in women, especially during reproductive age when menstrual-related hormonal fluctuations represent the most common migraine trigger. Indeed, over 50% of patients report a ..... see more

Source : https://link.springer.com/article/10.1007/s40122-021-00273-w

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  • 5 days 4 hours
    Very interesting study regarding menstrual migraine, which can be particulary hard to treat.
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The Role of Single Nucleotide Variants of NOS1, NOS2, and NOS3 Genes in the Development of the Phenotype of Migraine and Arterial Hypertension

Migraine (M) and arterial hypertension (AH) are very common diseases. Today, there are a number of studies confirming and explaining their comorbidity. We searched PubMed, Springer, Scopus, Web of Science, ..... see more

Source : https://www.mdpi.com/2076-3425/11/6/753

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Evidence that blood-CSF barrier transport, but not inflammatory biomarkers, change in migraine, while CSF sVCAM1 associates with migraine frequency and CSF fibrinogen - PubMed

The higher Q alb and Q fib ratios may indicate that the transport of these blood-derived proteins is disturbed at the BCSFB in persons with migraine. These changes most likely ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33724462/

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Evaluation of the oxidative and inflammatory profile of patients with migraine | Vaz | Ciência e Natura

Abu Bakar N, Tanprawate S, Lambru G et al. (2016) Quality of life in primary headache disorders: a review. Cephalalgia 36(1):67-91. https://doi.org/10.1177/03331 0241558 0099. Aebi H (1984) Catalase in vitro. ..... see more

Source : https://periodicos.ufsm.br/cienciaenatura/article/view/43366

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  • 2 weeks 6 days
    I am not sure if this would be feasible in treating patients daily.
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Clinical significance of serum sex hormones in postmenopausal women with vestibular migraine: potential role of estradiol - Bo Tang, Xiaojun Yu, Wei Jiang, Chuang Zhang, Tao Zhan, Yuqin He, 2021

This study aimed to investigate the role of sex hormones in postmenopausal women with vestibular migraine. This observational study included 242 female patients with vestibular migraine who were postmenopausal during ..... see more

Source : https://doi.org/10.1177/03000605211016379

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  • 2 weeks 6 days
    Estradiol is likely an important component.