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Timothy Tuel from Doctor Unite, Michael Evans from Doctor Unite Commented on a Post
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Huma Sheikh

One important treatment for migraine is preventive therapy. This can involve a number of different types of treatments, including oral medications, injections like botox or the new cGRP inhibitors, as well as neuromodulation techniques.

However, many people prefer not to take preventive therapy for a number of reasons, including side effects or difficulty with compliance. Even when taken correctly, a migraine preventive is considered successful if it reduces the frequency of migraine by 50%. This can mean some patients are still having significant migraines per month.

Complementary techniques including mindfulness, acupuncture and yoga have gained a lot of popularity in the last few years as being efficacious and a significant treatment modality as adjunct therapy for migraines.

Do you recommend mindfulness or other complementary techniques for migraine? What are your favorite resources to offer to patients?

References
Expert Rev Neurother. 2020 Mar; 20(3): 207–225.
Published online 2020 Feb 12. doi: 10.1080/14737175.2020.1715212
PMCID: PMC7213534
Mindfulness in Migraine. A narrative review
Rebecca Erwin Wells,* Elizabeth K. Seng, PhD, Robert R Edwards, Ph.D., David E Victorson, PhD, Charles R. Pierce, MS, Lauren Rosenberg, M.A., Vitaly Napadow, PhD, Director, and Zev Schuman-Olivier, MD, Director

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  • from Doctor Unite 2 days 9 hours
    On of the best migraine talks I ever presented discussed the "look" of a chronic migraine patient. He stated they will frequently have their arms crossed and appear to Show More
  • from Doctor Unite 2 days 11 hours
    I prefer meditation as a means of calming and stress reduction with a concomitant positive effect on migraine sufferers. I recommend many free apps but the main one I suggest Show More
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Comparative study of magnesium, sodium valproate, and concurrent magnesium-sodium valproate therapy in the prevention of migraine headaches: a randomized controlled double-blind trial

Objective This study aimed to assess the efficacy of concurrent magnesium-sodium valproate therapy and compare it with either magnesium or sodium valproate alone in migraine prophylaxis. Materials and methods This ..... see more

Source : https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1186/s10194-021-01234-6

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Naturalistic assessment of patterns and predictors of acute headache medication use among women with comorbid migraine and overweight or obesity

Lay Summary. Obesity may contribute to more severe migraine symptoms and negatively impact migraine treatment outcomes. The present study aimed to understand pa see more

Source : https://academic.oup.com/tbm/advance-article-abstract/doi/10.1093/tbm/ibab027/6211045

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Zinc supplementation affects favorably the frequency of migraine attacks: a double-blind randomized placebo-controlled clinical trial

Background Observational studies have shown a link between zinc deficiency and migraine headaches. We aimed to examine the effect of zinc supplementation on the characteristics of migraine attacks in patients ..... see more

Source : https://link.springer.com/article/10.1186/s12937-020-00618-9

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Biological and small molecule strategies in migraine therapy with relation to the CGRP family of peptides.

Biological and small molecule strategies in migraine therapy with relation to the CGRP family of peptides. Lars Edvinsson (GUEST EDITOR) Institute of Clinical Science in Lund, Lund University Author Profile ..... see more

Source : https://www.authorea.com/users/405590/articles/516532-biological-and-small-molecule-strategies-in-migraine-therapy-with-relation-to-the-cgrp-family-of-peptides

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Association Between Hemostatic Profile and Migraine: A Mendelian Randomization Analysis

Objective: To assess support for a causal relationship between hemostatic measures and migraine susceptibility using genetic instrumental analysis. Methods: Two-sample Mendelian randomization (MR) instrumental leveraging available genome-wide association study (GWAS) ..... see more

Source : https://n.neurology.org/content/early/2021/04/01/WNL.0000000000011931.abstract

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  • 1 week 3 days
    This is the new wave of providing specific patient-centric treatment.
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Abnormalities in cortical pattern of coherence in migraine detected using ultra high-density EEG

Abstract. Individuals with migraine generally experience photophobia and/or phonophobia during and between migraine attacks. Many different mechanisms have been see more

Source : https://doi.org/10.1093/braincomms/fcab061

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  • 1 week 3 days
    I wonder if this is able to be correlated clinically.
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Abnormalities in cortical pattern of coherence in migraine detected using ultra high-density EEG

Abstract. Individuals with migraine generally experience photophobia and/or phonophobia during and between migraine attacks. Many different mechanisms have been see more

Source : https://academic.oup.com/braincomms/advance-article/doi/10.1093/braincomms/fcab061/6208887

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from Commented on 's Post

52 yo F with a 36 year history of migraine. Has had good control with topiramate 100 mg daily and as needed treatment for breakthrough attacks with rizatriptan 10 mg. ..... see more

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  • 2 weeks 3 days
    I agree with the above, a triptan may still be a viable option. The other suggestions above also make good sense, I tend to stay away from lasmitidan as Show More
  • 3 weeks
    I will start by saying that I am not sure she cannot continue with rizatriptan given her infrequent use and assuming she has no symptoms when using it. There Show More
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Opening of ATP sensitive potassium channels causes migraine attacks with aura

Abstract. Migraine afflicts more than one billion individuals worldwide and is a leading cause of years lived with disability. In about a third of individuals w see more

Source : https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awab136/6188619

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  • 2 weeks 3 days
    This makes sense in regards to the cortical spreading depression.
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Common variants in KCNK5 and FHL5 genes contributed to the susceptibility of migraine without aura in Han Chinese population

A recent genome-wide meta study suggested that rs67338227 in the FHL5 gene and rs10456100 in the KCNK5 gene are associated with migraine from 27 population-based cohorts excluding Chinese population. see more

Source : https://www.nature.com/articles/s41598-021-86374-0

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  • 2 weeks 3 days
    This is an interesting study highlighting the fact that we are moving towards personalized medicine.
  • 2 weeks 5 days
    This study highlights the coming of personalized medicine based on genomics (at least in part). 2 SNPs were found to be associated with migraine without aura and a specific Show More
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Foods that stop nausea in its tracks. What helps with nausea naturally.

FOODS THAT STOP NAUSEA IN ITS TRACKS - 2021. @Neuralgroover Nausea is an extremely common symptom across a wide spectrum of diseases. It is one of the main symptoms in ..... see more

Source : https://virtualheadachespecialist.com/foods-that-stop-nausea-in-its-tracks/

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  • 2 weeks 3 days
    Ginger is a really effective treatment, esp in a tea.
  • 2 weeks 5 days
    Interesting blog which looks at non-medication interventions to help with nausea. Many folks find ginger quite helpful (either ginger slices or candied ginger, ginger ale or ginger tea). Show More

The impact of anti-CGRP monoclonal antibodies in resistant migraine patients: a real-world evidence observational study

Objective To evaluate the frequency and headache-related impact response to monoclonal antibodies against calcitonin gene-related peptide (CGRP) in a clinical sample of refractory migraine patients. Methods We included migraine patients ..... see more

Source : https://link.springer.com/article/10.1007/s00415-021-10523-8

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  • 2 weeks 3 days
    This validates previous studies showing that cGRP inhibitors work well in resistant patients.
  • from Doctor Unite 2 weeks 4 days
    This study shows proof that anti-CGRPs are effective at decreasing migraine days.

Migraine exacerbation during Ramadan fasting

Fasting for approximately 1 month is an obligatory practice for Muslims during the month of Ramadan. We attempted to evaluate the effect of the Ramadan fasting on the frequency of ..... see more

Source : https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1007/s10194-010-0242-z

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  • 2 weeks 3 days
    @Heidi Schwarz The date for Ramadan changes every year, Islam follows a lunar calendar so it is 10 days shorter than the solar calendar. Ramadan was in the winter Show More
  • from Doctor Unite 2 weeks 4 days
    I have had patients suffer from migraines during fasting. Some patients accept medication therapy, but others refuse because it is a sacrifice they are willing to make during Ramadan.

Migraine and handedness

Migraine is a typically unilateral disorder in adulthood; however, the reasons for painful lateralization have been little investigated. The possible influence of manual dominance was suggested. We aimed to investigate ..... see more

Source : https://link.springer.com/article/10.1007/s10072-021-05111-7

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  • from Doctor Unite 2 weeks 4 days
    Interesting study on correlation between handedness and migraines and side of attacks. I wonder that the data would look like for someone who is ambidextrous?
  • 1 month 3 weeks
    Interesting study, I am right handed but most of my migraines are on the left!

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  • from Doctor Unite 2 weeks 4 days
    The PNS method treats numerous pain conditions such as complex regional pain syndrome, diabetic peripheral neuropathy, foot pain, headache disorders, including episodic cluster headache, chronic migraine, occipital neuralgia ilioinguinal neuralgia, Show More
  • 2 weeks 5 days
    Very interesting because treatments for children have often been ineffective. It is frustrating that in the US, coverage for all of these interventions are usually denied by insurers even Show More

Cost-effectiveness of Erenumab Versus Surgical Trigger Site Deactivation for the Treatment of Migraine Headaches: A Systematic Review - PubMed

doi: 10.1097/SCS.0000000000007617. Online ahead of print. 1 Northwestern University Feinberg School of Medicine, Chicago, IL Department of Plastic Surgery Department of Neurology, University of California, Irvine School of Medicine, Orange, ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33710044/

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  • from Doctor Unite 2 weeks 4 days
    Another thing to consider are the risks, complications, and comorbidities for the surgical treatment. Would there be a need for second surgeries? Would the patient still require medications Show More
  • 2 weeks 5 days
    I find this study quite misleading on several fronts: 1. The data to support surgical trigger site deactivation for migraine is quite limited and biased 2. The estimates for the direct cost Show More

Diagnostic accuracy of serum Calcitonin Gene-Related Peptide | IJGM

Rabia Latif, 1 Nazish Rafique, 1 Lubna Al Asoom, 1 Ahmed A Alsunni, 1 Ayad Mohammed Salem, 1 Dinah Abdulhadi AlNoaimi, 2 Wasan Mohammed AlHarbi, 2 Ahad Yasir Shaikh, 2 ..... see more

Source : https://doi.org/10.2147/IJGM.S303350

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  • from Doctor Unite 2 weeks 4 days
    Interesting study on ApoE to help diagnose migraines. I agree with Heidi Schwarz, further studies and larger study/sample size would be more convincing. This would help with definitive Show More
  • 2 weeks 5 days
    Interesting but it seems to me that the authors have overstated the accuracy and relevance of their data. This is a very small study in a "monoculture". Without Show More
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The Comorbid Relationship Between Migraine and Asthma: A Systematic Review and Meta-Analysis of Population-Based Studies

Objective: Recent studies have indicated a pathophysiologic link between migraine and asthma. This meta-analysis aimed to comprehensively estimate the risk ratio for migraine in asthma as well as that of ..... see more

Source : https://doi.org/10.3389/fmed.2020.609528

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  • 2 weeks 5 days
    Interesting systematic review but to really prove a relationship between migraine and asthma, a prospective population based study is needed. Anecdotally, I often see migraine and asthma coexist which Show More
  • 1 month
    This is interesting since these are both chronic conditions with episodic attacks.