Test your understanding of the neurobiology and behavioral frameworks driving agitation in Alzheimer’s disease.
5 questions
Agitation in Alzheimer’s disease is linked to an imbalance between prefrontal and subcortical regions, causing emotional dysregulation and behavioral disinhibition due to:
Correct Answer: B
Impaired prefrontal control and heightened amygdala activation can disrupt emotion regulation and impulse control, contributing to agitation.
https://pmc.ncbi.nlm.nih.gov/articles/PMC12635648/pdf/wjp-15-11-109581.pdf
https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2023.1188603/full
https://pmc.ncbi.nlm.nih.gov/articles/PMC11799129/pdf/11011_2025_Article_1548.pdf
Which behavioral framework underlies most non-pharmacologic interventions for agitation in Alzheimer’s disease?
Correct Answer: A
The ABC model identifies behavioral triggers and outcomes, guiding tailored interventions.
Agitation in cognitive disorders may signal which acute medical condition triggered by infection or metabolic issues?
Correct Answer: C
Delirium, often caused by infection or metabolic imbalance, must be ruled out when assessing agitation in dementia.
During advanced Alzheimer’s disease, persistent agitation most commonly contributes to which caregiver outcome?
Correct Answer: D
Ongoing agitation significantly intensifies caregiving demands, often leading to burnout, emotional depletion, and loss of personal identity among caregivers.
https://www.mdpi.com/2039-4403/15/8/284
In Alzheimer’s disease, persistent agitation is most strongly associated with which patient-level consequence?
Agitation in Alzheimer’s disease is linked to worsening functional impairment, decreased quality of life, and increased risk of adverse outcomes as the disease progresses.
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